Silver plays no known natural biological role in humans, and possible health effects of silver are a disputed subject. Silver itself is not toxic but most silver salts are, and some may be carcinogenic. Silver and compounds containing silver (like colloidal silver) can be absorbed into the circulatory system and become deposited in various body tissues leading to a condition called argyria which results in a blue-grayish pigmentation of the skin, eyes, and mucous membranes. Although this condition does not otherwise harm a person’s health, it is disfiguring and usually permanent. Argyria is rare, and mild forms are sometimes mistaken for cyanosis.
Monitoring Exposure
Overexposure to silver can occur in workers in the metallurgical industry, persons taking silver-containing dietary supplements, patients who have received silver sulfadiazine treatment and individuals who accidentally or intentionally ingest silver salts. Silver concentrations in whole blood, plasma, serum or urine may be measured to monitor for safety in exposed workers, to confirm the diagnosis in potential poisoning victims or to assist in the forensic investigation in a case of fatal overdosage.
Use In Food
The safety of silver for use in food is disputed. Traditional Indian dishes sometimes include the use of decorative silver foil known as vark, and in various cultures silver dragée are used to decorate cakes, cookies, and other dessert items. The use of silver as a food additive is illegal in the United States and Australia.
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